Wolverine (Logan) and Deadpool (Wade Wilson) are two characters who frequently clash in Marvel comics and films. Though both are mutants and both endured unspeakable pain through the Weapon X program, tension almost always sparks between them. Here are a few reasons why Wolverine doesn’t particularly like Deadpool.
Opposite Personalities
Wolverine is a grim loner — a purebred berserker. He’s quiet, acts fast and hard, and almost never cracks a joke.
Deadpool, on the other hand, is his polar opposite: chatty, unpredictable, and maddeningly unserious. He never shuts up — even mid-fight — which drives Logan insane. If it weren’t for his regeneration, Wade would’ve died on their very first mission together.

Different Methods
Wolverine is a man of honor, even when he’s being brutal. He has an internal code, his own moral compass and taboos he never crosses.
Deadpool, meanwhile, will do anything — work for criminals, kill innocents if he thinks it’s justified, or act out just for fun. Just recall that post-credits scene where Wade “fixed the timeline” by visiting a maternity ward in Austria...
A Shared Past
Both characters came through the same secret program — Weapon X — where humans were turned into killing machines. This shared hell binds them, but also fuels their resentment: Deadpool reminds Logan of what he might have become had he completely lost his humanity. It’s disturbing — and infuriating.

The Comic Contrast
On a meta level, Deadpool constantly breaks the fourth wall, comments on the plot, and throws in endless pop culture references. Wolverine sees this as nonstop nonsense that doesn’t fit the film’s narrative.
And Deadpool constantly mocks Logan himself, making it impossible for the mutant to maintain his brooding image. Their conflict may seem hilarious to viewers — but from Logan’s perspective, it’s pure torment.
In every adaptation, they’ve had a few vicious showdowns. For example, in X-Men Origins: Wolverine, Deadpool’s character was distorted, and their on-screen meeting ended in a fight.

In later films, Ryan Reynolds (as Deadpool) regularly trolled Hugh Jackman (as Wolverine), and in their joint movie, they turned the screen into a bloodbath. Fortunately, since neither character can die, they eventually found a way to connect. For now, anyway — that’s a rhetorical question.
So Wolverine’s hatred of Deadpool is both a plot-driven and symbolic clash of opposites: silent rage versus unstoppable chaos.